Product Name :
2-hydroxy Estradiol (CAS 362-05-0)
Synonym :
1,3,5(10)-Estratriene-2,3-17β-triol; Estra-1,3,5(10)-triene-2,3,17-triol
Application :
2-hydroxy Estradiol is a compound with potential value in cancer research
CAS:
362-05-0
Purity:
≥95%
Molecular Weight:
288.38
Formula :
C18H24O3
Physical state:
Solid
solubility :
Soluble in ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and 1: 3 solution of ethanol: PBS (pH 7.2) (~0.25 mg/ml). Insoluble in water.
Shipping Condition :
Store at -20° C
Melting point:
190-191° C
SMILES:
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=C(C=C34)O)O
References:
and suppresses growth of lesions in a mouse model of endometriosis.P(t-Bu)3 Pd G2 uses | Becker, CM., et al. 2008. Am J Pathol. 172: 534-44. PMID: 18202195Evaluation of treatment for dry eye with 2-hydroxyestradiol using a dry eye rat model. | Higuchi, A., et al. 2016. Mol Vis. 22: 446-53. PMID: 27186071Tryptophan and kynurenine stimulate human decidualization via activating Aryl hydrocarbon receptor: Short title: Kynurenine action on human decidualization.4-bromo-2,6-dimethylpyridine uses | Wang, PC.PMID:33596172 , et al. 2020. Reprod Toxicol. 96: 282-292. PMID: 32781018Novel and potent biological antioxidants on membrane phospholipid peroxidation: 2-hydroxy estrone and 2-hydroxy estradiol. | Nakano, M., et al. 1987. Biochem Biophys Res Commun. 142: 919-24. PMID: 3827906Anovulation in female rats induced by neonatal administration of the catechol estrogens, 2-hydroxy-estradiol and 4-hydroxy-estradiol. | MacLusky, NJ., et al. 1983. Neuroendocrinology. 37: 321-7. PMID: 6196675Estrogen 2-, 4-, 6- or 16-hydroxylation by human follicles shown by gas chromatography-mass spectrometry associated with stable isotope dilution. | Dehennin, L., et al. 1984. J Steroid Biochem. 20: 465-71. PMID: 6708529Interaction of estradiol and 2-hydroxy-estradiol with histamine receptors at hypothalamic level. | Portaleone, P., et al. 1980. Brain Res. 187: 216-20. PMID: 7357469