Product Name :
1,3,9-Trimethylxanthine (CAS 519-32-4)

Synonym :
3,9-Dihydro-1,3,9-trimethyl-1H-purine-2,6-dione; 1,3,9-Trimethylxanthine; 9-Methyltheophylline; NSC 28332; EP Impurity C for Caffeine; Isocaffeine

Application :
1,3,9-Trimethylxanthine is an Adenosine A Receptor antagonist

CAS:
519-32-4

Purity:
≥97%

Molecular Weight:
194.19

Formula :
C8H10N4O2

Physical state:
Solid

solubility :
Soluble in water (>20 mg/mL).

Shipping Condition :
Store at room temperature

Melting point:
288° C (dec.)

SMILES:
CN1C=NC2=C1N(C(=O)N(C2=O)C)C

References:
:Dramatic differences in activity of purines metabolizing ecto-enzymes between mesenchymal stem cells isolated from human umbilical cord blood and umbilical cord tissue. | Roszek, K., et al. 2013. Biochem Cell Biol. 91: 519-25. PMID: 24219295Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by caffeine and related compounds.2248702-12-5 site | Rousseau, E., et al. 1988. Arch Biochem Biophys. 267: 75-86. PMID: 2848455Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog′s heart.N-Boc-PEG6-alcohol Purity | Chapman, RA.PMID:33461433 and Miller, DJ. 1974. J Physiol. 242: 615-34. PMID: 4375181Metabolism and distribution of labeled theophylline in the pregnant rat. Impairment of theophylline metabolism by pregnancy and absence of a blood-brain barrier in the fetus. | Arnaud, MJ., et al. 1982. Pediatr Res. 16: 167-71. PMID: 7063271Determination of caffeine and its metabolites in urine by high-performance liquid chromatography and capillary electrophoresis. | Rodopoulos, N. and Norman, A. 1994. Scand J Clin Lab Invest. 54: 305-15. PMID: 7939374Inhibition of inositol trisphosphate-induced calcium release by caffeine is prevented by ATP. | Missiaen, L., et al. 1994. Biochem J. 300 (Pt 1): 81-4. PMID: 8198556Elimination of theobromine metabolites in healthy adults. | Rodopoulos, N., et al. 1996. Scand J Clin Lab Invest. 56: 373-83. PMID: 8837245Elimination of theophylline metabolites in healthy adults. | Rodopoulos, N. and Norman, A. 1997. Scand J Clin Lab Invest. 57: 233-40. PMID: 9238759