Product Name :
Semaphorin 5A Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
SEMA5A antibody SEMAF antibody Semaphorin F antibody
Function :
Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human Semaphorin 5A 671-770/1074
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1073371-77-3 Price Avoid repeated freeze/thaw cycles.6-Bromoimidazo[1,2-a]pyrazin-2-amine In stock The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33506530 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
118 KDa
Positive control :