Product Name :
Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18]
Predicted band size :
19 kDa
Observed band size :
19 kDa
Synonyms:
18 kDa phosphoprotein antibody CFL 1 antibody CFL antibody CFL1 antibody COF1_HUMAN antibody Cofilin 1 antibody Cofilin 1 non muscle antibody Cofilin antibody Cofilin non muscle isoform antibody Cofilin-1 antibody 展开
Function :
Cofilin 1 (non-muscle; n-cofilin), also known as CFL1, is a human gene, part of the ADF/cofilin family. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. One group reports that reelin signaling leads to serine3-phosphorylation of cofilin-1, and this interaction may play a role in the reelin-related regulation of neuronal migration.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic phospho-peptide corresponding to residues surrounding Ser3 of human Cofilin aa 1-50.N-Mal-N-bis(PEG4-NH-Boc) Chemical name
Species reactivity:
Human, Rat, Monkey
Verify application:
WB
Coupling :
unconjugated
Clone number:
PSH07-18
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Buy3-Bromo-7-chloroquinoline Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.PMID:33538200
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 19 kDa
Positive control :
COS-1 cell lysate, C6 cell lysate, Jurkat cell lysate, MCF7 cell lysate, A431 cell lysate.