Product Name :
Poliovirus Receptor Recombinant Rabbit Monoclonal Antibody [JE45-53]
Predicted band size :
45 kDa
Observed band size :
75 kDa
Synonyms:
CD155 antibody CD155 antigen antibody FLJ25946 antibody HVED antibody mE4 antibody NECL 5 antibody Necl-5 antibody Necl5 antibody Nectin like 5 antibody Nectin like protein 5 antibody 展开
Function :
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155’s normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells.Formula of 77500-04-0 The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide.
Species reactivity:
Human
Verify application:
WB, IF-Cell
Coupling :
unconjugated
Clone number:
JE45-53
RRID:
AB_3072468
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.181434-36-6 structure Aliquot store at -20℃.PMID:33568427 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 45 kDa
Positive control :
HUVEC cell lysate, U87-MG cell lysate, A549 cell lysates, HUVEC.